Lab VIEW code for dynamic data collection (not yet available)
MATLAB codes for data analysis
If using EDGAR for force recording, please cite the following paper:
If using the GAITOR Suite software (including AGATHAv2) for gait analysis, please cite one of the following paper(s):
- B.Y. Jacobs, K. Dunnigan, M. Pires-Fernandes, and K.D. Allen. Unique spatiotemporal and dynamic gait compensations in the rat monoiodoacetate injection and medial meniscus transection models of knee osteoarthritis. Osteoarthritis Cartilage, (2016).
If using the GAITOR Suite software (including AGATHAv2) for gait analysis, please cite one of the following paper(s):
- AGATHAv2 with ColorThresholder updates and EDGAR integration
- B.Y. Jacobs, E.H. Lakes, A.J. Reiter, S.P. Lake, T.R. Ham, N.D. Leipzig, S.L. Porvasnik, C.E. Schmidt, R.A. Wachs, and K.D. Allen. The Open Source GAITOR Suite for Rodent Gait Analysis. Scientific Reports, (2018).
- B.Y. Jacobs, E.H. Lakes, A.J. Reiter, S.P. Lake, T.R. Ham, N.D. Leipzig, S.L. Porvasnik, C.E. Schmidt, R.A. Wachs, and K.D. Allen. The Open Source GAITOR Suite for Rodent Gait Analysis. Scientific Reports, (2018).
- AGATHA version 1 and original algorithm description:
- H.E. Kloefkorn, T.R. Pettengill, S.M. Turner, K.A. Streeter, E.J. Gonzalez-Rothi, E, D.D. Fuller, and K.D. Allen. Automated Gait Analysis Through Hues and Areas (AGATHA): A Method to Characterize the Spatiotemporal Pattern of Rat Gait, Ann Biomed Eng, (2016) 1-15.
Pre-Clinical Gait Analysis Reviews - Methods and Recommendations
- Jacobs, B. Y., Kloefkorn, H. E., & Allen, K. D. (2014). Gait analysis methods for rodent models of osteoarthritis. Current pain and headache reports, 18(10), 1-11.
- E.H. Lakes, K.D. Allen, Gait analysis methods for rodent models of arthritic disorders: reviews and recommendations. Osteoarthritis Cartilage, 24(11), (2016) 1837-1849.
- Allen KD, Adams SB Jr., and Setton LA (2010), “Evaluating Intra-articular Drug Delivery for the Treatment of Osteoarthritis in a Rat Model,” Tissue Engineering Part B: Reviews, 16(1), pgs. 81-92.
Examples of Gait Analysis in Pre-Clinical Models of Knee Osteoarthritis
- K.D. Allen, T.M. Griffin, R.M. Rodriguiz, W.C. Wetsel, V.B. Kraus, ... & L.A Setton (2009). Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. Arthritis Rheum, 60(9), 2684-93.
- K.D. Allen, S.B. Adams, B.A. Mata, M.F. Shamji, E. Gouze, L. Jing, ... & L.A Setton (2011), Gait and behavior in an IL1β‐mediated model of rat knee arthritis and effects of an IL1 antagonist, J Orthop Res, 29(5), 694-703.
- K.D. Allen, B.A. Mata, M.A. Gabr, J.L. Huebner, S.B. Adams, V.B. Kraus, and L.A. Setton (2012) Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis. Arthritis Res Ther, 14(R78), 1-14.
- H.E. Kloefkorn, B.Y. Jacobs, A.M. Loye, K.D. Allen (2015), Spatiotemporal gait compensations following medial collateral ligament and medial meniscus injury in the rat: correlating gait patterns to joint damage. Arthritis Res Ther, 17(1), 287.
- B.Y. Jacobs, K. Dunnigan, M. Pires-Fernandes, K.D. Allen (2016), Unique spatiotemporal and dynamic gait compensations in the rat monoiodoacetate injection and medial meniscus transection models of knee osteoarthritis. Osteoarthritis Cartilage.
- E.H. Lakes and K.D. Allen (2018), “Quadrupedal rodent gait compensations in a low dose monoiodoacetate model of osteoarthritis.” Gait & Posture. Jun;63:73-79.